Spandex fetishism is a fetishistic attraction to people wearing stretch fabrics or, in certain cases, to the garments themselves.

Many people refer to spandex fetishism as Lycra fetishism, Lycra being INVISTA's trademark for their own brand of spandex fabric.

One reason why spandex and other tight fabrics may be fetishised is that the garment forms a "second skin," acting as a fetishistic surrogate for the wearer's own skin. Wearers of skin-tight nylon and cotton spandex garments can appear naked or coated in a shiny or matte substance like paint. The tightness of the garments may also be seen as sexual bondage. Another reason is that nylon-spandex fabric (preferred by many spandex fetishists) is often produced with a very smooth and silk-like finish, which lends a tactile dimension to the fetish - as well as a visual one.